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Literature summary extracted from

  • McClatchie, T.; Meredith, M.; Ouedraogo, M.O.; Slow, S.; Lever, M.; Mann, M.R.W.; Zeisel, S.H.; Trasler, J.M.; Baltz, J.M.
    Betaine is accumulated via transient choline dehydrogenase activation during mouse oocyte meiotic maturation (2017), J. Biol. Chem., 292, 13784-13794 .
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.99.1 3,3-dimethylbutanol completely blocks activity Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
1.1.99.1 Mus musculus Q8BJ64
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.99.1 kidney
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Mus musculus
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1.1.99.1 oocyte CHDH transcripts and protein are found in oocytes. CHDH becomes highly active during oocyte meiotic maturation and is inactive after fertilization. Endogenous betaine is present at low levels in germinal vesicle stage mouse oocytes before ovulation and reaches high levels in the mature, ovulated egg Mus musculus
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Synonyms

EC Number Synonyms Comment Organism
1.1.99.1 CHDH
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Mus musculus